Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 11/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540467 | 0.81 | KDM4E (0.52) | OPRK1OPRM1OPRD1KDM4EALDH1A1 | |
| SCHEMBL8537772 | 0.80 | ALDH1A1 (0.47) | OPRK1OPRM1OPRD1KDM4EALDH1A1 | |
| SCHEMBL8538897 | 0.76 | ALDH1A1 (0.66) | OPRK1OPRM1KDM4EALDH1A1GAA | |
| SCHEMBL8538305 | 0.76 | OPRK1 (0.48) | OPRK1OPRM1OPRD1KDM4EALDH1A1 | |
| SCHEMBL31029043 | 0.73 | OPRK1 (0.53) | OPRK1OPRM1OPRD1KDM4EALDH1A1 | |
| SCHEMBL31043597 | 0.73 | OPRK1 (0.53) | OPRK1OPRM1OPRD1KDM4EALDH1A1 | |
| Carbamic Acid SCHEMBL8540366 | 0.73 | RECQL (0.46) | OPRK1OPRM1OPRD1KDM4EALDH1A1 | |
| SCHEMBL8541194 | 0.72 | DRD2 (0.59) | OPRK1OPRM1OPRD1KDM4EALDH1A1 | |
| SCHEMBL8539779 | 0.71 | KDM4E (0.60) | OPRK1OPRM1OPRD1KDM4EALDH1A1 | |
| SCHEMBL29059534 | 0.70 | PRKCI (0.57) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7278103-A | — | — | None | — | — | JP | disclosed |
| JP-H07278103-A | (PYRROLIDINYL)PHENYL CARBAMATE AND INTERMEDIATE, PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL | HOECHST ROUSSEL PHARMACEUT INC | 1995-10-24 | — | — | JP | disclosed |