Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 8/20 | 0.34 |
| ▸ | RAB9A | P51151 | 8/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542579 | 0.88 | CA1 (0.39) | SMN1; SMN2KMT2AMEN1CA1CA2 | |
| SCHEMBL8542777 | 0.78 | CA1 (0.44) | SMN1; SMN2KMT2AMEN1CA1CA2 | |
| SCHEMBL8538198 | 0.78 | CA1 (0.38) | SMN1; SMN2KMT2AMEN1CA1CA2 | |
| SCHEMBL8538094 | 0.72 | CES2 (0.42) | KMT2AMEN1CA1CA2CA4 | |
| SCHEMBL8539554 | 0.72 | CA1 (0.38) | SMN1; SMN2KMT2AMEN1CA1CA2 | |
| SCHEMBL8537256 | 0.71 | L3MBTL1 (0.40) | SMN1; SMN2KMT2AMEN1CA1CA2 | |
| SCHEMBL6777725 | 0.71 | RAB9A (0.50) | SMN1; SMN2KMT2AMEN1CA1CA2 | |
| SCHEMBL8538385 | 0.71 | KCNK3 (0.43) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8538807 | 0.70 | KCNK3 (0.42) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8542600 | 0.70 | ERCC5 (0.41) | SMN1; SMN2KMT2AMEN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |