Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9145496 | 0.89 | LMNA (0.38) | LMNASMN1; SMN2AKR1C3AKR1C2CYP1A2 | |
| SCHEMBL9208674 | 0.87 | CYP1A2 (0.33) | LMNASMN1; SMN2CYP1A2ALDH1A1KDM4E | |
| SCHEMBL9214341 | 0.85 | CYP1A2 (0.32) | LMNASMN1; SMN2CYP1A2ALDH1A1KDM4E | |
| SCHEMBL9217071 | 0.85 | ADORA3 (0.36) | LMNASMN1; SMN2CYP1A2ALDH1A1KDM4E | |
| SCHEMBL9122561 | 0.85 | ALOX5 (0.32) | CYP1A2GAA | |
| SCHEMBL8537289 | 0.85 | LMNA (0.35) | LMNASMN1; SMN2AKR1C3AKR1C2CYP1A2 | |
| SCHEMBL9558483 | 0.84 | AKR1C3 (0.38) | LMNASMN1; SMN2AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL9208329 | 0.83 | ADORA3 (0.35) | CYP1A2ALDH1A1ADORA3 | |
| SCHEMBL9209462 | 0.82 | ALDH1A1 (0.31) | ALDH1A1ADORA3 | |
| SCHEMBL9214908 | 0.82 | LGALS8 (0.36) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517215-B1 | Pyrimidine or triazine derivative, process for preparing the same and herbicide using the same | UBE INDUSTRIES (JP) | 1998-09-02 | — | — | EP | claimed |
| US-5387575-A | Pyrimidine derivatives, process for preparing the same and herbicide using the same | UBE INDUSTRIES, LTD. (JP) | 1995-02-07 | — | — | US | claimed |
| EP-0517215-A1 | Pyrimidine or triazine derivative, process for preparing the same and herbicide using the same | UBE INDUSTRIES, LTD. (JP) | 1992-12-09 | — | — | EP | claimed |
| EP-0517215-B1 | Pyrimidine or triazine derivative, process for preparing the same and herbicide using the same | UBE INDUSTRIES (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5529977-A | A 3-ALKOXYBUTYRYLIMIDAZOLE COMPOUND | UBE INDUSTRIES, LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| US-5387575-A | Pyrimidine derivatives, process for preparing the same and herbicide using the same | UBE INDUSTRIES, LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0517215-A1 | Pyrimidine or triazine derivative, process for preparing the same and herbicide using the same | UBE INDUSTRIES, LTD. (JP) | 1992-12-09 | — | — | EP | disclosed |