SCHEMBL9214908

SCHEMBL9214908

COc1cc(OC)nc(SC(C(=O)NS(=O)(=O)c2ccccn2)C(C)(C)OC)n1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 1/20 0.36
NLRP3 Q96P20 1/20 0.36
EDNRB P24530 7/20 0.35
EDNRA P25101 7/20 0.35
TXNRD1 Q16881 1/20 0.34
GLO1 Q04760 2/20 0.34
CYP17A1 P05093 1/20 0.34
TP53 P04637 1/20 0.33
GLA P06280 1/20 0.33
MAPT P10636 1/20 0.33
GRM4 Q14833 1/20 0.33
ADORA2A P29274 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9213410 0.93 LGALS8 (0.36) LGALS8NLRP3EDNRBEDNRATXNRD1
SCHEMBL9206886 0.84 PPARA (0.39) LGALS8NLRP3TXNRD1GLO1CYP17A1
SCHEMBL8538415 0.82 LMNA (0.37) GAA
SCHEMBL9385685 0.81 LMNA (0.35) TP53GLAMAPTGAA
SCHEMBL9209579 0.81 EDNRB (0.50) EDNRBEDNRA
SCHEMBL9208674 0.79 CYP1A2 (0.33) EDNRBEDNRAGAA
SCHEMBL9217071 0.77 ADORA3 (0.36) TP53GLAMAPTGAA
SCHEMBL9122561 0.77 ALOX5 (0.32) GAA
SCHEMBL9214341 0.77 CYP1A2 (0.32) TP53GLAMAPTGAA
SCHEMBL9208329 0.76 ADORA3 (0.35) EDNRBEDNRATP53GLAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0567014-B1 Sulfonamide derivative, process for preparing the same and herbicide using the same UBE INDUSTRIES (JP) 1995-07-12 EP claimed
US-5376620-A Sulfonamide derivative, process for preparing the same and herbicide using the same UBE INDUSTRIES, LTD. (JP) 1994-12-27 US claimed
EP-0567014-A1 Sulfonamide derivative, process for preparing the same and herbicide using the same UBE INDUSTRIES, LTD. (JP) 1993-10-27 EP claimed
JP-6009620-A None JP disclosed
EP-0567014-B1 Sulfonamide derivative, process for preparing the same and herbicide using the same UBE INDUSTRIES (JP) 1995-07-12 EP disclosed
US-5376620-A Sulfonamide derivative, process for preparing the same and herbicide using the same UBE INDUSTRIES, LTD. (JP) 1994-12-27 US disclosed
JP-H069620-A 3-ALKOXY-N-PYRIDYLSULALKANOIC ACID AMIDE DERIVATIVE, ITS PRODUCTION AND HERBICIDE UBE IND LTD 1994-01-18 JP disclosed
EP-0567014-A1 Sulfonamide derivative, process for preparing the same and herbicide using the same UBE INDUSTRIES, LTD. (JP) 1993-10-27 EP disclosed