Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 3/20 | 0.36 |
| ▸ | KDM4A | O75164 | 3/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.36 |
| ▸ | KDM3B | Q7LBC6 | 3/20 | 0.36 |
| ▸ | HIF1AN | Q9NWT6 | 3/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 7/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538467 | 0.83 | PPARG (0.37) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL8535732 | 0.79 | KDM4E (0.39) | NPC1RAB9ASMN1; SMN2PTGS2 | |
| SCHEMBL8539946 | 0.72 | MCL1 (0.38) | NPC1RAB9ASMN1; SMN2KDM6BKDM4A | |
| SCHEMBL8538683 | 0.70 | KMT2A (0.39) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL11787842 | 0.69 | ALDH1A1 (0.45) | RAB9ASMN1; SMN2CA12CA1CA2 | |
| SCHEMBL7375775 | 0.69 | HTR2B (0.50) | CA12CA1CA2CA7CA13 | |
| SCHEMBL8336040 | 0.69 | KDM6B (0.30) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL8535971 | 0.69 | KDM4E (0.36) | NPC1RAB9ASMN1; SMN2KDM6BKDM4A | |
| SCHEMBL6957097 | 0.69 | CYSLTR1 (0.41) | SMN1; SMN2PTPRCPTPN2PTPN1PTPN6 | |
| SCHEMBL8538469 | 0.69 | ALOX5 (0.38) | NPC1RAB9ASMN1; SMN2KDM6BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |