Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.67 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Mercaptobenzimidazole SCHEMBL705730 | 0.80 | ALDH1A1 (1.00) | ALDH1A1PSMB8HSD17B10MAPTTDP1 | |
| 2-Mercaptobenzimidazole SCHEMBL29360590 | 0.80 | ALDH1A1 (1.00) | ALDH1A1PSMB8HSD17B10MAPTTDP1 | |
| 2-Mercaptobenzimidazole SCHEMBL29562524 | 0.78 | ALDH1A1 (0.94) | ALDH1A1PSMB8HSD17B10MAPTTDP1 | |
| SCHEMBL3063883 | 0.75 | KMT2A (1.00) | ALDH1A1PSMB8HSD17B10MAPTTDP1 | |
| SCHEMBL31414198 | 0.75 | KMT2A (1.00) | ALDH1A1PSMB8HSD17B10MAPTTDP1 | |
| SCHEMBL31414202 | 0.75 | KMT2A (1.00) | ALDH1A1PSMB8HSD17B10MAPTTDP1 | |
| 2-Mercaptobenzimidazole SCHEMBL7550230 | 0.69 | ALDH1A1 (0.75) | ALDH1A1PSMB8HSD17B10MAPTTDP1 | |
| SCHEMBL4957425 | 0.69 | ALDH1A1 (0.56) | ALDH1A1PSMB8HSD17B10MAPTTDP1 | |
| SCHEMBL11323975 | 0.69 | KDM4E (0.61) | ALDH1A1PSMB8HSD17B10MAPTTDP1 | |
| SCHEMBL2777925 | 0.69 | DAO (0.60) | ALDH1A1HSD17B10MAPTTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9867377-B2 | Composition comprising a biological control agent and an insecticide | BAYER CROPSCIENCE AG (DE) | 2018-01-16 | — | — | US | claimed |
| US-20170265479-A1 | COMPOSITION COMPRISING BIOLOGICAL CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2017-09-21 | — | — | US | claimed |
| US-20150148230-A1 | COMPOSITIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE | BAYER CROPSCIENCE AG (DE) | 2015-05-28 | — | — | US | claimed |
| WO-2023135582-A1 | NEW STEREORETENTIVE RUTHENIUM COMPLEXES, METHOD OF THEIR PREPARATION, INTERMEDIATES USED IN THIS METHOD AND USE OF NEW STEREORETENTIVE RUTHENIUM COMPLEXES IN OLEFIN METATHESIS REACTIONS | UNIWERSYTET WARSZAWSKI (PL) | 2023-07-20 | — | — | WO | disclosed |
| EP-2880033-B1 | CYCLIC UREA- OR LACTAM-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA LP (US) | 2020-06-17 | — | — | EP | disclosed |
| EP-3564240-A1 | PIPERIDINE INTERMEDIATES | Purdue Pharma L.P. (US) | 2019-11-06 | — | — | EP | disclosed |
| US-9598447-B2 | Phosphorus-substituted quinoxaline-type piperidine compounds and uses thereof | PURDUE PHARMA L.P. (US) | 2017-03-21 | — | — | US | disclosed |
| US-9527840-B2 | Substituted-quinoxaline-type piperidine compounds and the uses thereof | PURDUE PHARMA L.P. (US) | 2016-12-27 | — | — | US | disclosed |
| EP-3101018-A1 | SUBSTITUTED-QUINOXALINE-TYPE-PIPERIDINE COMPOUNDS AND THE USES THEREOF | Purdue Pharma L.P. (US) | 2016-12-07 | — | — | EP | disclosed |
| EP-2654751-B1 | PHOSPHORUS-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF | PURDUE PHARMA LP (US) | 2016-11-23 | — | — | EP | disclosed |
| EP-2433937-B1 | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | PURDUE PHARMA LP (US) | 2016-06-29 | — | — | EP | disclosed |
| WO-2012085648-A1 | PHOSPHORUS-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF | PURDUE PHARMA L.P. (US) | 2012-06-28 | — | — | WO | disclosed |
| EP-2433937-A1 | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | Purdue Pharma LP (US) | 2012-03-28 | — | — | EP | disclosed |
| EP-2433935-A1 | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | Purdue Pharma LP (US) | 2012-03-28 | — | — | EP | disclosed |
| EP-2433936-A1 | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | Purdue Pharma LP (US) | 2012-03-28 | — | — | EP | disclosed |
| US-20100216726-A1 | Substituted-Quinoxaline-Type Piperidine Compounds and the Uses Thereof | PURDUE PHARMA L.P. (US) | 2010-08-26 | — | — | US | disclosed |
| EP-0614471-B1 | VINYL CHLORIDE AND HETEROCYCLIC THIONE FUNCTIONAL POLYURETHANE POLYMER BLENDS AND THEIR USE IN MAGNETIC RECORDING MEDIA | MINNESOTA MINING & MFG (US) | 1997-05-07 | — | — | EP | disclosed |
| EP-0492963-B1 | Heterocyclic thione functional polyurethane polymers and their use in magnetic recording media | MINNESOTA MINING & MFG (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5246788-A | VINYL CHLORIDE AND HETEROCYCLIC THIONE FUNCTIONAL POLYURETHANE POLYMER BLENDS AND THEIR USE IN MAGNETIC RECORDING MEDIA | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-09-21 | — | — | US | disclosed |
| EP-0492963-A2 | Heterocyclic thione functional polyurethane polymers and their use in magnetic recording media | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216726-A1 | Substituted-Quinoxaline-Type Piperidine Compounds and the Uses Thereof | P2RX4, P2RX5, P2RX3 | ALDH1A1 889/4885PSMB8 2972/4885HSD17B10 4631/4885 |
| US-20150148230-A1 | COMPOSITIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE | DDT, ACHE, BROX | ALDH1A1 2817/4885PSMB8 478/4885HSD17B10 2226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.