Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 5/20 | 0.32 |
| ▸ | HTT | P42858 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538637 | 0.88 | MAPT (0.35) | ACHEMAPTTHRBHTTALDH1A1 | |
| SCHEMBL8543278 | 0.87 | TXNRD1 (0.38) | ACHEMAPTTHRBHTTALDH1A1 | |
| SCHEMBL27358000 | 0.86 | ALDH1A1 (0.33) | ACHEMAPTTHRBHTTALDH1A1 | |
| SCHEMBL8538802 | 0.85 | TXNRD1 (0.40) | MAPTTHRBHTTALDH1A1LMNA | |
| SCHEMBL8542635 | 0.85 | TXNRD1 (0.36) | MAPTTHRBHTTALDH1A1LMNA | |
| SCHEMBL6935106 | 0.84 | SLC9A1 (0.36) | — | |
| SCHEMBL8542948 | 0.84 | TXNRD1 (0.39) | MAPTTHRBHTTALDH1A1LMNA | |
| SCHEMBL8537187 | 0.84 | TXNRD1 (0.39) | MAPTTHRBHTTALDH1A1LMNA | |
| SCHEMBL8542680 | 0.81 | TAS1R3 (0.31) | — | |
| SCHEMBL8539018 | 0.79 | TAS1R3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |