Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.52 |
| ▸ | RORC | P51449 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539183 | 0.90 | HTR6 (0.52) | HTR6RORCATMPKMALOX5 | |
| SCHEMBL8542321 | 0.88 | PTGDR2 (0.56) | HTR6RORCMAPTTP53PTGDR2 | |
| SCHEMBL19150402 | 0.84 | KMO (0.55) | MAPTATMALOX5EPHX2 | |
| SCHEMBL10165467 | 0.78 | RORC (0.50) | RORCMAPTTP53 | |
| SCHEMBL8537431 | 0.78 | TBXAS1 (0.58) | HTR6RORCPKMTP53PTGDR2 | |
| SCHEMBL8539323 | 0.75 | TBXAS1 (0.61) | RORCMAPTPKMTP53PTGDR2 | |
| SCHEMBL8539547 | 0.75 | TBXAS1 (0.53) | MAPTPTGDR2 | |
| SCHEMBL3138249 | 0.74 | HTR6 (0.77) | HTR6MAPTPKMHPGD | |
| SCHEMBL13139532 | 0.74 | MEN1 (0.47) | HTR6MAPTTP53 | |
| SCHEMBL1102270 | 0.74 | AVPR2 (0.59) | MAPTPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715627-B1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | PFIZER LTD (GB) | 1998-09-09 | — | — | EP | claimed |