Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539549 | 0.87 | KDM4E (0.47) | MAPTKCNK3LMNAMEN1KMT2A | |
| SCHEMBL8538091 | 0.86 | KMT2A (0.46) | MAPTKCNK3MEN1KMT2ARAB9A | |
| SCHEMBL8542887 | 0.84 | KCNK3 (0.46) | KCNK3KMT2ARAB9AKCNK9ALDH1A1 | |
| SCHEMBL8539479 | 0.84 | ALDH1A1 (0.46) | MAPTKCNK3LMNAMEN1KMT2A | |
| SCHEMBL8541777 | 0.81 | ALDH1A1 (0.42) | MAPTKCNK3LMNAMEN1KMT2A | |
| SCHEMBL7506955 | 0.80 | KMT2A (0.50) | MAPTKCNK3MEN1KMT2APKM | |
| SCHEMBL7497380 | 0.80 | KMT2A (0.50) | MAPTKCNK3MEN1KMT2APKM | |
| SCHEMBL8540369 | 0.77 | KDM4E (0.41) | MAPTKCNK3LMNAMEN1KMT2A | |
| Bicarbonate SCHEMBL7469511 | 0.76 | MAPT (0.65) | MAPTKCNK3LMNAPTGS1MEN1 | |
| SCHEMBL5896056 | 0.74 | LMNA (0.61) | MAPTKCNK3LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |