Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539549 | 0.90 | KDM4E (0.47) | KMT2AMEN1KCNK3NPC1RAB9A | |
| SCHEMBL8542887 | 0.87 | KCNK3 (0.46) | KMT2AKCNK3NPC1RAB9AHPGD | |
| SCHEMBL8539479 | 0.87 | ALDH1A1 (0.46) | KMT2AMEN1KCNK3NPC1RAB9A | |
| SCHEMBL8539492 | 0.86 | MAPT (0.49) | KMT2AMEN1KCNK3RAB9AALDH1A1 | |
| SCHEMBL8541777 | 0.83 | ALDH1A1 (0.42) | KMT2AMEN1KCNK3NPC1RAB9A | |
| SCHEMBL7506955 | 0.83 | KMT2A (0.50) | KMT2AMEN1KCNK3NPC1SNCA | |
| SCHEMBL7497380 | 0.83 | KMT2A (0.50) | KMT2AMEN1KCNK3NPC1SNCA | |
| SCHEMBL8540369 | 0.79 | KDM4E (0.41) | KMT2AMEN1KCNK3NPC1RAB9A | |
| SCHEMBL8544854 | 0.76 | RAB9A (0.42) | KMT2AMEN1KCNK3NPC1RAB9A | |
| SCHEMBL10430611 | 0.72 | AKR1C3 (0.48) | KMT2AMEN1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |