Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 7/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541777 | 0.92 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2NPC1ALOX12RAB9A | |
| SCHEMBL8539549 | 0.90 | KDM4E (0.47) | ALDH1A1SMN1; SMN2NPC1ALOX12RAB9A | |
| SCHEMBL8540369 | 0.88 | KDM4E (0.41) | ALDH1A1SMN1; SMN2NPC1ALOX12RAB9A | |
| SCHEMBL8538091 | 0.87 | KMT2A (0.46) | ALDH1A1NPC1RAB9AHPGDKCNK3 | |
| SCHEMBL8542887 | 0.87 | KCNK3 (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL8539492 | 0.84 | MAPT (0.49) | ALDH1A1RAB9ALMNAKCNK3KCNK9 | |
| SCHEMBL7506955 | 0.83 | KMT2A (0.50) | NPC1KCNK3KCNK9KMT2AMEN1 | |
| SCHEMBL7497380 | 0.83 | KMT2A (0.50) | NPC1KCNK3KCNK9KMT2AMEN1 | |
| SCHEMBL8544854 | 0.76 | RAB9A (0.42) | ALDH1A1SMN1; SMN2NPC1ALOX12RAB9A | |
| SCHEMBL2165320 | 0.73 | MEN1 (0.50) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |