Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 5/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541777 | 0.93 | ALDH1A1 (0.42) | KDM4EKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL8542887 | 0.88 | KCNK3 (0.46) | KDM4EKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL8539479 | 0.88 | ALDH1A1 (0.46) | KDM4EKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL8539549 | 0.84 | KDM4E (0.47) | KDM4EKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL7497380 | 0.79 | KMT2A (0.50) | KCNK3KCNK9NPC1MAPTKMT2A | |
| SCHEMBL7506955 | 0.79 | KMT2A (0.50) | KCNK3KCNK9NPC1MAPTKMT2A | |
| SCHEMBL8538091 | 0.79 | KMT2A (0.46) | KDM4EKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL8539492 | 0.77 | MAPT (0.49) | KCNK3KCNK9RAB9AALDH1A1NPSR1 | |
| SCHEMBL8544854 | 0.73 | RAB9A (0.42) | KCNK3KCNK9NPC1RAB9AALDH1A1 | |
| SCHEMBL8538020 | 0.69 | ITGB3 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |