Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250795 | 0.73 | OPRK1 (0.47) | OPRK1OPRM1OPRD1ALDH1A1GAA | |
| SCHEMBL8540467 | 0.72 | KDM4E (0.52) | OPRK1OPRM1OPRD1ALDH1A1GAA | |
| SCHEMBL8537772 | 0.71 | ALDH1A1 (0.47) | OPRK1OPRM1OPRD1ALDH1A1GAA | |
| Carbamic Acid SCHEMBL9226170 | 0.71 | PRCP (0.81) | RECQLPRCPGAATSHRKMT2A | |
| SCHEMBL8540323 | 0.71 | ALDH1A1 (0.45) | OPRK1OPRM1OPRD1ALDH1A1GAA | |
| SCHEMBL28007086 | 0.69 | PRCP (0.76) | RECQLPRCPGAATSHRKMT2A | |
| Urea SCHEMBL28007088 | 0.69 | PRCP (0.81) | RECQLPRCPGAATSHRKMT2A | |
| SCHEMBL8540362 | 0.68 | LIPE (0.52) | OPRK1OPRM1OPRD1ALDH1A1KDM4E | |
| SCHEMBL16495226 | 0.68 | TACR1 (0.46) | OPRK1OPRM1ALDH1A1KDM4ETSHR | |
| Urea SCHEMBL27886692 | 0.68 | GAA (0.81) | RECQLPRCPGAATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671388-B1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5591856-A | CHEMICAL INTERMEDIATES, TREATMENT OF ALZHEIMER'S DISEASE | HOECHST ROUSSEL PHARMACEUTICALS INC. (US) | 1997-01-07 | — | — | US | disclosed |
| US-5554750-A | TO RELIEVE MEMORY DYSFUNCTIONS; TREATMENT OF ALZHEMER*S | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1996-09-10 | — | — | US | disclosed |
| EP-0671388-A1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5405845-A | Administering to relieve memory dysfunction; treatment of Alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-04-11 | — | — | US | disclosed |
| US-5338739-A | Memory dysfunction relieving compounds | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-08-16 | — | — | US | disclosed |