Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | CCR1 | P32246 | 10/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540315 | 0.79 | ALDH1A1 (0.43) | ACHEKCNH2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8539296 | 0.78 | ACHE (0.50) | ACHEOPRM1OPRK1OPRD1 | |
| SCHEMBL8542776 | 0.72 | ACHE (0.58) | ACHEOPRM1OPRK1OPRD1 | |
| SCHEMBL8544539 | 0.72 | PARP14 (0.53) | KDM4EALDH1A1 | |
| SCHEMBL8542915 | 0.71 | OPRK1 (0.50) | ACHEKDM4EALDH1A1OPRM1OPRK1 | |
| SCHEMBL9316755 | 0.70 | OPRM1 (0.52) | ACHEOPRM1OPRK1OPRD1 | |
| SCHEMBL8538305 | 0.69 | OPRK1 (0.48) | ACHEKDM4EALDH1A1SMN1; SMN2OPRM1 | |
| SCHEMBL8539614 | 0.67 | ACHE (0.52) | ACHEALDH1A1SMN1; SMN2OPRM1OPRK1 | |
| SCHEMBL8538682 | 0.67 | DRD4 (0.54) | ALDH1A1OPRM1OPRK1 | |
| SCHEMBL8539650 | 0.67 | ACHE (0.46) | ACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671388-B1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-06-10 | — | — | EP | claimed |
| EP-0671388-A1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-09-13 | — | — | EP | claimed |
| US-5338739-A | Memory dysfunction relieving compounds | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-08-16 | — | — | US | claimed |