Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539491 | 0.74 | KCNK3 (0.44) | KMT2ANPC1RAB9AKCNK3KCNK9 | |
| SCHEMBL8542018 | 0.70 | CYP1A2 (0.45) | KMT2AMAPK1NPC1RAB9APLAU | |
| SCHEMBL8541231 | 0.69 | PARP1 (0.40) | KMT2ANPC1RAB9AKCNK3KCNK9 | |
| SCHEMBL8538122 | 0.68 | MMP1 (0.40) | KMT2AMAPK1NPC1RAB9APLAU | |
| SCHEMBL8538568 | 0.66 | ALDH1A1 (0.46) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL8430807 | 0.65 | CA12 (0.35) | RAB9AMAPT | |
| SCHEMBL8431259 | 0.65 | RXFP1 (0.43) | KMT2ANPC1RAB9APLAUMEN1 | |
| SCHEMBL8542779 | 0.64 | MAPT (0.43) | KMT2AMAPK1NPC1RAB9AMEN1 | |
| SCHEMBL8431432 | 0.64 | RAB9A (0.36) | KMT2AMAPK1NPC1RAB9APLAU | |
| SCHEMBL8430795 | 0.64 | CA12 (0.40) | RAB9APLAUPOLBALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |