Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 10/20 | 0.57 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.57 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24672584 | 0.98 | TLR8 (0.58) | DNM2TLR8NOS3NOS2ALDH1A1 | |
| SCHEMBL9313985 | 0.93 | TLR8 (0.65) | DNM2TLR8NOS3NOS2ALDH1A1 | |
| SCHEMBL12963699 | 0.85 | NOS3 (0.55) | DNM2TLR8NOS3NOS2ALDH1A1 | |
| SCHEMBL13989410 | 0.83 | TLR8 (0.61) | DNM2TLR8ALDH1A1MAPK1LMNA | |
| SCHEMBL13309860 | 0.83 | TLR8 (0.61) | DNM2TLR8ALDH1A1MAPK1LMNA | |
| SCHEMBL13309832 | 0.83 | TLR8 (0.61) | DNM2TLR8ALDH1A1MAPK1LMNA | |
| SCHEMBL13309844 | 0.83 | TLR8 (0.61) | DNM2TLR8ALDH1A1MAPK1LMNA | |
| SCHEMBL13309816 | 0.83 | TLR8 (0.61) | DNM2TLR8ALDH1A1MAPK1LMNA | |
| SCHEMBL13309799 | 0.83 | TLR8 (0.61) | DNM2TLR8ALDH1A1MAPK1LMNA | |
| SCHEMBL13329946 | 0.81 | DNM2 (0.81) | DNM2TLR8ALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843947-A | N-pyridyl carboxamides and derivatives | ADIR ET COMPAGNIE (FR) | 1998-12-01 | — | — | US | disclosed |
| EP-0587499-B1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR (FR) | 1998-04-29 | — | — | EP | disclosed |
| US-5712294-A | N-pyridyl carboxamides and derivatives | ADIR ET COMPAGNIE (FR) | 1998-01-27 | — | — | US | disclosed |
| EP-0684241-B1 | N-pyridyl carboxamide derivatives, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1997-08-27 | — | — | EP | disclosed |
| EP-0684241-A1 | N-pyridyl carboxamide derivatives, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-11-29 | — | — | EP | disclosed |
| US-5395834-A | Antiarthritic agents or cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1995-03-07 | — | — | US | disclosed |
| US-5393775-A | Administering a (2-chromanyl)alkylcarboxylic acid for disorders connected with peroxidation processes | ADIR ET COMPAGNIE (FR) | 1995-02-28 | — | — | US | disclosed |
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |
| EP-0587499-A1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR ET COMPAGNIE (FR) | 1994-03-16 | — | — | EP | disclosed |
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | disclosed |