Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539549 | 0.83 | KDM4E (0.47) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL7506955 | 0.79 | KMT2A (0.50) | KMT2AMEN1NPC1KCNK3KCNK9 | |
| SCHEMBL7497380 | 0.79 | KMT2A (0.50) | KMT2AMEN1NPC1KCNK3KCNK9 | |
| SCHEMBL8541777 | 0.77 | ALDH1A1 (0.42) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL8539479 | 0.76 | ALDH1A1 (0.46) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL8542887 | 0.76 | KCNK3 (0.46) | RAB9AKMT2ANPC1ALDH1A1HPGD | |
| SCHEMBL8538091 | 0.76 | KMT2A (0.46) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL7864209 | 0.74 | HPSE (0.62) | KMT2AMEN1NR1H4ITGB3ITGA2B | |
| SCHEMBL8539492 | 0.74 | MAPT (0.49) | RAB9AKMT2AMEN1ALDH1A1KCNK3 | |
| SCHEMBL8540369 | 0.73 | KDM4E (0.41) | RAB9AKMT2AMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |