Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546712 | 0.94 | L3MBTL1 (0.45) | ALDH1A1HSD17B10USP2MAPTHTT | |
| SCHEMBL9035936 | 0.91 | ALDH1A1 (0.46) | ALDH1A1HSD17B10MAPTHTTKDM4E | |
| SCHEMBL8543496 | 0.89 | TRPM8 (0.39) | ALDH1A1HSD17B10USP2MAPTHTT | |
| SCHEMBL8543410 | 0.87 | TRPM8 (0.42) | ALDH1A1HSD17B10MAPTHTTKDM4E | |
| SCHEMBL8547197 | 0.86 | TRPM8 (0.41) | ALDH1A1HSD17B10MAPTHTTKDM4E | |
| SCHEMBL8546335 | 0.85 | HSD17B10 (0.44) | ALDH1A1HSD17B10USP2MAPTHTT | |
| SCHEMBL8543834 | 0.84 | ALDH1A1 (0.40) | ALDH1A1HSD17B10MAPTKDM4EL3MBTL1 | |
| SCHEMBL8551330 | 0.83 | TRPM8 (0.39) | ALDH1A1HSD17B10MAPTHTTKDM4E | |
| SCHEMBL8546592 | 0.83 | ALDH1A1 (0.40) | ALDH1A1HSD17B10MAPTHTTKDM4E | |
| SCHEMBL8549346 | 0.81 | LMNA (0.53) | ALDH1A1HSD17B10MAPTHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |