Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548084 | 0.88 | PPARD (0.39) | KDM4EALDH1A1HPGDMAPTTP53 | |
| SCHEMBL8543410 | 0.85 | TRPM8 (0.42) | TRPM8KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL9035936 | 0.83 | ALDH1A1 (0.46) | TRPM8KDM4EALDH1A1CYP2C9MAPT | |
| SCHEMBL8544938 | 0.83 | ALDH1A1 (0.46) | TRPM8KDM4EALDH1A1MAPTTP53 | |
| SCHEMBL8546712 | 0.81 | L3MBTL1 (0.45) | TRPM8KDM4EALDH1A1MAPTTP53 | |
| SCHEMBL8543496 | 0.81 | TRPM8 (0.39) | TRPM8KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL9036139 | 0.80 | TRPM8 (0.37) | TRPM8KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8549346 | 0.79 | LMNA (0.53) | TRPM8KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL8545901 | 0.78 | ALDH1A1 (0.43) | TRPM8KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8549230 | 0.78 | TRPM8 (0.42) | TRPM8ALDH1A1HPGDCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |