Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | USP19 | O94966 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545335 | 0.81 | HDAC3 (0.54) | ALDH1A1POLBSMN1; SMN2CYP19A1TBXAS1 | |
| SCHEMBL8699085 | 0.81 | PKM (0.49) | USP7ALDH1A1POLBHRH4HMOX2 | |
| SCHEMBL8540164 | 0.81 | CYP19A1 (0.50) | CYP19A1 | |
| SCHEMBL8540312 | 0.80 | GRIN2B (0.55) | ALDH1A1POLBNPC1TSHRTBXAS1 | |
| SCHEMBL8540527 | 0.79 | HDAC3 (0.52) | CYP19A1TBXAS1 | |
| SCHEMBL8538696 | 0.78 | FAAH (0.50) | ALDH1A1POLBTBXAS1 | |
| SCHEMBL9030351 | 0.74 | POLB (0.51) | USP7ALDH1A1POLBHRH4CACNA2D1 | |
| SCHEMBL8545661 | 0.74 | GRIN2B (0.46) | ALDH1A1CYP19A1TBXAS1 | |
| SCHEMBL8541116 | 0.74 | FAAH (0.57) | ALDH1A1POLBNPC1SMN1; SMN2TBXAS1 | |
| SCHEMBL30703468 | 0.72 | ALDH1A1 (0.64) | USP7ALDH1A1POLBCACNA2D1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |