⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10596180 | 0.78 | — | — | |
| SCHEMBL8545478 | 0.72 | DUT (0.36) | — | |
| SCHEMBL22235774 | 0.72 | LIPG (0.54) | — | |
| SCHEMBL7328315 | 0.72 | KCNH2 (0.30) | — | |
| SCHEMBL7328833 | 0.71 | LMNA (0.30) | — | |
| SCHEMBL7302023 | 0.69 | KCNH2 (0.30) | — | |
| SCHEMBL9988351 | 0.68 | — | — | |
| SCHEMBL24072 | 0.68 | AOC3 (0.34) | — | |
| SCHEMBL198568 | 0.68 | NR3C1 (0.36) | — | |
| SCHEMBL9987449 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659747-B1 | Branched aminothiazole derivatives process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1998-04-01 | — | — | EP | disclosed |
| EP-0659747-A1 | Branched aminothiazole derivatives process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1995-06-28 | — | — | EP | disclosed |