Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 3/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545761 | 1.00 | APP (0.45) | APPALDH1A1LMNAPOLBGAA | |
| SCHEMBL8550306 | 0.79 | MAOB (0.62) | ALDH1A1KDM4EMEN1KMT2AMAOB | |
| SCHEMBL8545664 | 0.76 | KDM4E (0.53) | ALDH1A1KDM4EMEN1KMT2AMAOB | |
| SCHEMBL28208757 | 0.74 | MAOB (0.66) | ALDH1A1POLBHPGDKDM4EMEN1 | |
| SCHEMBL28411136 | 0.73 | CASP3 (0.57) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL28209630 | 0.68 | CASP3 (0.61) | ALDH1A1LMNAMAPTL3MBTL1KDM4E | |
| SCHEMBL24470576 | 0.67 | CASP3 (0.69) | ALDH1A1LMNAMAPTHPGDL3MBTL1 | |
| SCHEMBL8545670 | 0.67 | SLC26A3 (0.48) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL7403324 | 0.64 | MAOB (0.57) | ALDH1A1KDM4EMEN1KMT2AMAOB | |
| SCHEMBL31556120 | 0.64 | ALDH1A1 (0.78) | ALDH1A1LMNAPOLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623607-B1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0623607-A1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1994-11-09 | — | — | EP | disclosed |