Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 7/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500164 | 0.87 | CTRB1 (0.49) | MMP12MMP13NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6498025 | 0.76 | CTRB1 (0.47) | MMP12MMP13NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8550797 | 0.75 | ALDH1A1 (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8543203 | 0.73 | CTRB1 (0.57) | CA9CA12CA1CTRB1 | |
| SCHEMBL8545838 | 0.71 | ELANE (0.37) | ALDH1A1CA2CA9CA12CA1 | |
| SCHEMBL8545278 | 0.68 | ELANE (0.47) | NPC1RAB9AALDH1A1CTRB1 | |
| SCHEMBL8551382 | 0.68 | ELANE (0.47) | NPC1RAB9AALDH1A1CTRB1 | |
| SCHEMBL8549217 | 0.68 | ELANE (0.41) | SMN1; SMN2ALDH1A1MEN1KMT2ACTRB1 | |
| SCHEMBL8546542 | 0.67 | ELANE (0.42) | RAB9AALDH1A1CTRB1 | |
| SCHEMBL7659173 | 0.66 | ATM (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |