Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 9/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543702 | 0.88 | ACHE (0.49) | MEN1KMT2AACHEALDH1A1BCHE | |
| SCHEMBL10969744 | 0.76 | ALDH1A1 (0.68) | MEN1KMT2ACTSLSTSCTSK | |
| SCHEMBL15264157 | 0.74 | CTSK (0.64) | MEN1KMT2ACTSLSTSCTSK | |
| SCHEMBL8546496 | 0.73 | NR3C1 (0.47) | ALDH1A1 | |
| SCHEMBL8547009 | 0.73 | NR3C1 (0.48) | — | |
| SCHEMBL11900347 | 0.73 | KMT2A (0.67) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27399132 | 0.72 | ALDH1A1 (0.62) | MEN1KMT2ACTSLSTSCTSK | |
| SCHEMBL9427407 | 0.72 | CYP19A1 (0.58) | MEN1KMT2AACHECTSLSTS | |
| SCHEMBL28668394 | 0.71 | ALDH1A1 (0.57) | MEN1KMT2AACHEALDH1A1GAA | |
| SCHEMBL8549308 | 0.71 | ATM (0.48) | MEN1KMT2AACHEBCHEATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |