Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 11/20 | 0.45 |
| ▸ | BCHE | P06276 | 5/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546973 | 0.79 | MEN1 (0.53) | L3MBTL1MEN1KMT2A | |
| SCHEMBL27689452 | 0.78 | ALOX5 (0.51) | ALOX5MEN1KMT2A | |
| SCHEMBL8550223 | 0.75 | ALOX5 (0.56) | ALOX5KMT2A | |
| SCHEMBL6037547 | 0.75 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL8543702 | 0.75 | ACHE (0.49) | ATMTDP1L3MBTL1ACHEBCHE | |
| SCHEMBL9374562 | 0.74 | ATM (0.49) | ATMTDP1L3MBTL1ALOX5ACHE | |
| SCHEMBL8550646 | 0.73 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL259581 | 0.72 | L3MBTL1 (0.59) | ATMTDP1L3MBTL1PBRM1 | |
| SCHEMBL9372536 | 0.72 | ALOX5 (0.53) | ALOX5MEN1KMT2A | |
| SCHEMBL8546874 | 0.72 | CES2 (0.60) | ATMTDP1L3MBTL1PBRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |