Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550683 | 0.87 | DGAT2 (0.41) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8307605 | 0.70 | MAPK1 (0.39) | ALDH1A1MAPTKDM4EHPGDTDP1 | |
| SCHEMBL615685 | 0.70 | F11 (0.53) | F11MASP2KLKB1 | |
| SCHEMBL4437800 | 0.69 | ALDH1A1 (0.52) | ALDH1A1MAPTNPSR1KDM4EHPGD | |
| SCHEMBL8308344 | 0.68 | ALDH1A1 (0.47) | ALDH1A1MAPTNPSR1KDM4EHPGD | |
| SCHEMBL9000063 | 0.67 | ALDH1A1 (0.56) | ALDH1A1MAPTNPSR1KDM4EHPGD | |
| SCHEMBL13245154 | 0.67 | ALDH1A1 (0.49) | ALDH1A1MAPTNPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL29792718 | 0.66 | MYC (0.51) | F11ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL3006745 | 0.66 | MYC (0.51) | F11ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL4925703 | 0.65 | NPC1 (0.58) | ALDH1A1MAPTNPSR1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623607-B1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1998-07-15 | — | — | EP | disclosed |
| US-5504213-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |
| EP-0623607-A1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1994-11-09 | — | — | EP | disclosed |