Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546253 | 0.87 | F11 (0.37) | ALDH1A1TSHRKDM4ESMN1; SMN2MAPT | |
| SCHEMBL8546281 | 0.71 | MAPT (0.58) | ALDH1A1KDM4ESMN1; SMN2MAPTNPC1 | |
| SCHEMBL9000063 | 0.67 | ALDH1A1 (0.56) | ALDH1A1TSHRKDM4EMAPTCYP3A4 | |
| SCHEMBL8324883 | 0.67 | NPC1 (0.48) | ALDH1A1TSHRKDM4ESMN1; SMN2MAPT | |
| SCHEMBL13245154 | 0.65 | ALDH1A1 (0.49) | ALDH1A1KDM4ESMN1; SMN2MAPTNPC1 | |
| SCHEMBL8307605 | 0.65 | MAPK1 (0.39) | ALDH1A1TSHRKDM4EMAPTCYP2C19 | |
| SCHEMBL4440201 | 0.64 | NPC1 (0.60) | DGAT2ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL4925703 | 0.63 | NPC1 (0.58) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL16547892 | 0.63 | MAPT (0.57) | ALDH1A1TSHRKDM4ESMN1; SMN2MAPT | |
| SCHEMBL30608274 | 0.63 | KDM4E (0.72) | ALDH1A1TSHRKDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504213-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | claimed |
| EP-0623607-B1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1998-07-15 | — | — | EP | disclosed |
| US-5504213-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |
| EP-0623607-A1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1994-11-09 | — | — | EP | disclosed |