Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701274 | 0.94 | KDM4E (0.53) | CPB1HPGDSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL8540140 | 0.90 | HPGD (0.57) | CPB1HPGDSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL8540312 | 0.87 | GRIN2B (0.55) | CPB1KDM4ECHRNB2CHRNA4CHRNB4 | |
| SCHEMBL8541319 | 0.82 | HPGD (0.50) | HPGDSMN1; SMN2NPC1TDP1ALDH1A1 | |
| SCHEMBL9037390 | 0.82 | CPB1 (0.42) | CPB1HPGDSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL8538696 | 0.81 | FAAH (0.50) | CPB1KDM4EMAPK1ALDH1A1POLB | |
| SCHEMBL8541116 | 0.81 | FAAH (0.57) | CPB1SMN1; SMN2KDM4ENPC1TDP1 | |
| SCHEMBL9031024 | 0.80 | PKM (0.53) | CPB1SMN1; SMN2KDM4EMAPK1CHRNB2 | |
| SCHEMBL8545138 | 0.80 | SMN1; SMN2 (0.67) | CPB1HPGDSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL8546498 | 0.79 | HPGD (0.65) | CPB1HPGDSMN1; SMN2KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| EP-0705258-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |