Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518196 | 0.89 | NPSR1 (0.39) | SMN1; SMN2MAPTENPP3GAATHRB | |
| SCHEMBL8548358 | 0.88 | ALDH1A1 (0.46) | SMN1; SMN2LMNAMAPTADORA2AENPP3 | |
| Hydrochloric Acid SCHEMBL8547922 | 0.88 | NPSR1 (0.39) | SMN1; SMN2MAPTENPP3GAATHRB | |
| SCHEMBL8553998 | 0.85 | KDR (0.37) | SMN1; SMN2LMNAMAPTENPP3GAA | |
| SCHEMBL8553708 | 0.83 | LMNA (0.35) | SMN1; SMN2LMNAMAPTADORA2AENPP3 | |
| SCHEMBL8552079 | 0.81 | SMN1; SMN2 (0.34) | SMN1; SMN2LMNAMAPTENPP3GAA | |
| SCHEMBL8551148 | 0.78 | ENPP3 (0.38) | SMN1; SMN2LMNAMAPTENPP3KDR | |
| SCHEMBL8518058 | 0.77 | ADORA2A (0.36) | ADORA2AKDRALDH1A1 | |
| Hydrochloric Acid SCHEMBL8546924 | 0.76 | ADORA2A (0.36) | ADORA2AKDR | |
| SCHEMBL8546417 | 0.75 | MEN1 (0.36) | SMN1; SMN2LMNAMAPTADORA2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |