Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.36 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548684 | 0.92 | RAB9A (0.42) | GABRA1GABRG2GABRB3GABRA3TSHR | |
| SCHEMBL8547249 | 0.88 | AURKA (0.45) | TSHRNPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL8548181 | 0.86 | TRPA1 (0.43) | TSHRNPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL8544014 | 0.86 | ELOVL1 (0.39) | TSHRNPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL8542280 | 0.84 | AURKA (0.47) | NPC1RAB9AL3MBTL1POLBELOVL1 | |
| SCHEMBL8548719 | 0.83 | MRGPRX1 (0.40) | TSHRNPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL8541261 | 0.82 | ELOVL1 (0.36) | TSHRNPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL8545027 | 0.82 | ELOVL1 (0.36) | TSHRNPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL8546438 | 0.82 | CNR1 (0.38) | TSHRNPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL8543586 | 0.82 | RAB9A (0.51) | TSHRNPC1RAB9AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411963-A | Plant fungicides, miticides, insecticides | DOWELANCO (US) | 1995-05-02 | — | — | US | claimed |
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |
| US-5411963-A | Plant fungicides, miticides, insecticides | DOWELANCO (US) | 1995-05-02 | — | — | US | disclosed |