Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548285 | 0.92 | GABRA1 (0.39) | RAB9ATSHRNPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8547249 | 0.90 | AURKA (0.45) | RAB9ATSHRNPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8548181 | 0.88 | TRPA1 (0.43) | RAB9ATSHRNPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8544014 | 0.88 | ELOVL1 (0.39) | RAB9ATSHRNPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8546847 | 0.88 | RAB9A (0.41) | RAB9ATSHRNPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8542280 | 0.85 | AURKA (0.47) | RAB9ANPC1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL8548719 | 0.85 | MRGPRX1 (0.40) | RAB9ATSHRNPC1L3MBTL1LMNA | |
| SCHEMBL8545027 | 0.84 | ELOVL1 (0.36) | RAB9ATSHRNPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8546438 | 0.84 | CNR1 (0.38) | RAB9ATSHRNPC1L3MBTL1CNR1 | |
| SCHEMBL8541261 | 0.84 | ELOVL1 (0.36) | RAB9ATSHRNPC1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052379-C | Quinazoline derisatives | DOWELANCO (US) | 2000-05-17 | — | — | CN | disclosed |
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |