Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 4/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548592 | 0.86 | THRA (0.50) | THRATHRBPLA2G2ASMN1; SMN2MAPT | |
| SCHEMBL8551491 | 0.85 | THRA (0.49) | THRATHRBPLA2G2ASMN1; SMN2MAPT | |
| SCHEMBL8549089 | 0.85 | CCNE2 (0.38) | THRATHRBCCNB2CCNE2CDK1 | |
| SCHEMBL8546447 | 0.84 | HPGD (0.46) | SMN1; SMN2MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL8548248 | 0.82 | THRA (0.49) | THRATHRBSMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL12765211 | 0.75 | CCNE2 (0.48) | THRATHRBCCNB2CCNE2CDK1 | |
| SCHEMBL8549251 | 0.75 | THRA (0.55) | THRATHRBPLA2G2ASMN1; SMN2AKR1C2 | |
| SCHEMBL28809090 | 0.73 | RAB9A (0.47) | PLA2G2ASMN1; SMN2MAPTL3MBTL1CYP1A2 | |
| SCHEMBL16364900 | 0.73 | THRB (0.54) | THRATHRBMAPTL3MBTL1CYP1A2 | |
| SCHEMBL8378478 | 0.72 | TSHR (0.51) | SMN1; SMN2MAPTL3MBTL1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |