Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 4/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.38 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.38 |
| ▸ | CDK1 | P06493 | 3/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548540 | 0.85 | THRA (0.44) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL8546447 | 0.74 | HPGD (0.46) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28809090 | 0.74 | RAB9A (0.47) | MAPTPLA2G2APTPN11L3MBTL1TDP1 | |
| SCHEMBL8548592 | 0.71 | THRA (0.50) | MAPTPLA2G2APTPN11L3MBTL1AKR1C2 | |
| SCHEMBL8551491 | 0.71 | THRA (0.49) | MAPTPLA2G2AL3MBTL1THRATHRB | |
| SCHEMBL12765211 | 0.68 | CCNE2 (0.48) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL8548248 | 0.68 | THRA (0.49) | MAPTL3MBTL1TDP1THRATHRB | |
| SCHEMBL12646896 | 0.67 | CCNE2 (0.47) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL27932429 | 0.67 | LMNA (0.46) | MAPTTDP1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL11573931 | 0.67 | LMNA (0.57) | PTPN11L3MBTL1THRATHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |