Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.45 |
| ▸ | CTSK | P43235 | 11/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553275 | 0.89 | GRM5 (0.41) | CTSSCTSKKCNH2GRM5 | |
| SCHEMBL7009339 | 0.84 | KMO (0.47) | CTSSKDM4EKMOCCNA2CDK2 | |
| SCHEMBL8471818 | 0.81 | PSD (0.41) | CTSSKDM4EP2RY1CYP1A2CYP2C9 | |
| SCHEMBL8548872 | 0.79 | POLB (0.43) | CTSSCTSKKDM4ESCN9AP2RY1 | |
| SCHEMBL8552730 | 0.77 | POLB (0.41) | CTSSCTSKKDM4EP2RY1CYP1A2 | |
| SCHEMBL8553832 | 0.77 | TRPV1 (0.43) | CTSSCTSKKDM4ESCN9A | |
| SCHEMBL8547908 | 0.76 | POLB (0.41) | CTSSCTSKKDM4ESCN9AP2RY1 | |
| SCHEMBL8773215 | 0.76 | CYP1A2 (0.50) | CTSSKDM4EP2RY1CYP1A2CYP2C9 | |
| SCHEMBL8546808 | 0.76 | POLB (0.43) | CTSSCTSKKDM4ESCN9AP2RY1 | |
| SCHEMBL8552758 | 0.75 | KIF11 (0.42) | CTSSCTSKKCNH2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820996-A1 | Herbicidal cyanopyridines | American Cyanamid Company (US) | 1998-01-28 | — | — | EP | claimed |
| EP-0820996-A1 | Herbicidal cyanopyridines | American Cyanamid Company (US) | 1998-01-28 | — | — | EP | disclosed |