Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481071 | 0.84 | HTR1D (0.51) | DRD2 | |
| SCHEMBL8721056 | 0.83 | MCHR1 (0.38) | FAAHMTNR1AGAA | |
| SCHEMBL8547967 | 0.77 | MAPT (0.46) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL8553038 | 0.76 | UBE2M (0.42) | UBE2MDCUN1D1NPC1RAB9AMEN1 | |
| SCHEMBL8551288 | 0.75 | HTR1D (0.40) | MEN1KMT2ADRD2SLC6A4 | |
| SCHEMBL8552156 | 0.74 | HTR1D (0.34) | MTNR1ADRD2SLC6A4 | |
| SCHEMBL8552293 | 0.74 | LMNA (0.42) | MEN1KMT2ADRD2SLC6A4HSD17B10 | |
| SCHEMBL8708863 | 0.74 | UBE2M (0.47) | UBE2MDCUN1D1 | |
| SCHEMBL8553042 | 0.73 | UBE2M (0.47) | UBE2MDCUN1D1 | |
| SCHEMBL8552460 | 0.73 | DRD2 (0.38) | DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |