SCHEMBL8549263

SCHEMBL8549263

O=[N+]([O-])C=C(NCC1CCOC1)N1CCCC1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
NAMPT P43490 15/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8549261 1.00 ALDH1A1 (0.35) ALDH1A1NAMPT
SCHEMBL8551553 0.75 ACHE (0.37) NAMPT
SCHEMBL8551550 0.75 ACHE (0.37) NAMPT
SCHEMBL8547465 0.74 BCHE (0.33) NAMPT
SCHEMBL8547468 0.74 BCHE (0.33) NAMPT
SCHEMBL8545753 0.74 NAMPT (0.31) NAMPT
SCHEMBL8544397 0.74 ALDH1A1 (0.38) ALDH1A1NAMPT
SCHEMBL8544399 0.74 ALDH1A1 (0.38) ALDH1A1NAMPT
SCHEMBL8545760 0.74 NAMPT (0.31) NAMPT
SCHEMBL2194777 0.68 NAMPT (0.34) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3324955-B1 COMPOSITION COMPRISING FIPRONIL AND DINOTEFURAN FOR USE IN AMETHOD OF CONTROLLING FLEAS IN NON HUMAN MAMMALS CEVA SANTE ANIMALE (FR) 2026-04-29 EP disclosed
US-11134685-B2 Compositions and uses thereof for controlling ectoparasites in non-human mammals Ceva Santé Animale (FR) 2021-10-05 US disclosed
EP-3358953-B1 VETERINARY COMPOSITIONS FOR THE CONTROL OF PHLEBOTOMES CEVA SANTE ANIMALE (FR) 2021-05-19 EP disclosed
US-10952988-B2 Methods for controlling the spread of dirofilariosis Ceva Santé Animale (FR) 2021-03-23 US disclosed
US-20200163339-A1 COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS Ceva Santé Animale (FR) 2020-05-28 US disclosed
US-20180279620-A1 VETERINARY COMPOSITIONS FOR SANDFLY CONTROL CEVA SANTE ANIMALE (FR) 2018-10-04 US disclosed
US-20180235926-A1 METHODS FOR CONTROLLING THE SPREAD OF DIROFILARIOSIS Ceva Santè Animale (FR) 2018-08-23 US disclosed
US-20180213790-A1 COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS Ceva Santé Animale (FR) 2018-08-02 US disclosed
EP-3324955-A1 COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAIN MAMMALS Ceva Sante Animale (FR) 2018-05-30 EP disclosed
EP-3259990-A1 METHODS FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS Ceva Sante Animale (FR) 2017-12-27 EP disclosed
WO-2017108904-A1 METHODS AND MEANS FOR THE ERADICATION OF FLEAS CEVA SANTE ANIMALE (FR) 2017-06-29 WO disclosed
WO-2017060641-A1 VETERINARY COMPOSITIONS FOR SANDFLY CONTROL CEVA SANTE ANIMALE (FR) 2017-04-13 WO disclosed
WO-2017017021-A1 COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAIN MAMMALS CEVA SANTE ANIMALE (FR) 2017-02-02 WO disclosed
EP-3120846-A1 COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS Ceva Sante Animale (FR) 2017-01-25 EP disclosed
EP-0649845-B1 Furanyl insecticide MITSUI CHEMICALS INC (JP) 1998-07-22 EP disclosed
US-5532365-A NITROGUANIDINE COMPOUNDS AS INSECTICIDES MITSUI TOATSU CHEMICALS, INC. (JP) 1996-07-02 US disclosed
US-5434181-A FOR USE IN AGRICULTURAL CHEMICALS MITSUI TOATSU CHEMICALS, INC. (JP) 1995-07-18 US disclosed
EP-0649845-A1 Furanyl insecticide MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11134685-B2 Compositions and uses thereof for controlling ectoparasites in non-human mammals NISCH, NAMPT, TYR ALDH1A1 4256/4885NAMPT 2/4885
US-20180235926-A1 METHODS FOR CONTROLLING THE SPREAD OF DIROFILARIOSIS NISCH, DDT, TNNT2 ALDH1A1 4056/4885NAMPT 75/4885
US-10952988-B2 Methods for controlling the spread of dirofilariosis NISCH, DDT, TNNT2 ALDH1A1 4056/4885NAMPT 75/4885
US-20180279620-A1 VETERINARY COMPOSITIONS FOR SANDFLY CONTROL NISCH, SGMS1, SGMS2 ALDH1A1 4285/4885NAMPT 72/4885
US-20180213790-A1 COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS NISCH, NAMPT, TYR ALDH1A1 4256/4885NAMPT 2/4885
US-20200163339-A1 COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS NISCH, NAMPT, TYR ALDH1A1 4256/4885NAMPT 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.