Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544266 | 0.87 | HPGD (0.54) | PKMALDH1A1SMN1; SMN2NPC1F2 | |
| SCHEMBL8549494 | 0.85 | ALDH1A1 (0.56) | PKMALDH1A1SMN1; SMN2F2MAPT | |
| SCHEMBL8549691 | 0.84 | CNR2 (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8549703 | 0.84 | CNR2 (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8543051 | 0.83 | RAB9A (0.56) | ALDH1A1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL8549486 | 0.77 | ALDH1A1 (0.56) | PKMALDH1A1SMN1; SMN2F2MAPT | |
| SCHEMBL8543196 | 0.77 | HSD11B1 (0.62) | PKMALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11738645 | 0.76 | HPGD (0.69) | ALDH1A1KMT2AEPHX2MEN1 | |
| SCHEMBL8543046 | 0.75 | KMT2A (0.52) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL8543030 | 0.75 | KMT2A (0.52) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |