Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544266 | 0.85 | HPGD (0.54) | HSD11B1ALDH1A1P2RX7PKMSMN1; SMN2 | |
| SCHEMBL8549494 | 0.83 | ALDH1A1 (0.56) | HSD11B1ALDH1A1P2RX7PKMSMN1; SMN2 | |
| SCHEMBL8548918 | 0.82 | HSD11B1 (0.54) | HSD11B1ALDH1A1P2RX7KDM4ELMNA | |
| SCHEMBL8543192 | 0.82 | HSD11B1 (0.54) | HSD11B1ALDH1A1P2RX7KDM4ELMNA | |
| SCHEMBL8543051 | 0.79 | RAB9A (0.56) | ALDH1A1LMNASMN1; SMN2TSHRKMT2A | |
| SCHEMBL8549705 | 0.77 | PKM (0.54) | ALDH1A1PKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8544257 | 0.76 | HSD11B1 (0.46) | HSD11B1ALDH1A1P2RX7KDM4ELMNA | |
| SCHEMBL8544264 | 0.76 | HSD11B1 (0.46) | HSD11B1ALDH1A1P2RX7KDM4ELMNA | |
| SCHEMBL8549491 | 0.75 | KMT2A (0.47) | HSD11B1ALDH1A1KDM4ELMNAHTT | |
| SCHEMBL8549484 | 0.75 | KMT2A (0.47) | HSD11B1ALDH1A1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |