Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545150 | 0.84 | GAA (0.43) | KDM4EMAPTLMNAALDH1A1TRPM8 | |
| SCHEMBL8548816 | 0.80 | POLB (0.53) | KDM4EMAPTHPGDLMNAALDH1A1 | |
| SCHEMBL8546712 | 0.79 | L3MBTL1 (0.45) | KDM4EMAPTALDH1A1TRPM8TP53 | |
| SCHEMBL8663874 | 0.79 | TRPM8 (0.43) | KDM4EMAPTHPGDLMNAALDH1A1 | |
| SCHEMBL8548183 | 0.77 | SMN1; SMN2 (0.43) | KDM4EHPGDLMNAALDH1A1TRPM8 | |
| SCHEMBL8549346 | 0.75 | LMNA (0.53) | KDM4EMAPTHPGDLMNAALDH1A1 | |
| SCHEMBL8550467 | 0.74 | CYP1A2 (0.50) | KDM4EMAPTALDH1A1TRPM8KMT2A | |
| SCHEMBL8550254 | 0.74 | TRPM8 (0.46) | MAPTLMNAALDH1A1TRPM8TP53 | |
| SCHEMBL8543398 | 0.74 | TRPM8 (0.44) | KDM4EMAPTHPGDLMNAALDH1A1 | |
| SCHEMBL9035936 | 0.73 | ALDH1A1 (0.46) | KDM4EMAPTLMNAALDH1A1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |