Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549735 | 0.86 | MAPT (0.35) | ALDH1A1KDM4ELMNAMAPTTSHR | |
| SCHEMBL8666788 | 0.81 | TRPM8 (0.41) | ALDH1A1HSD17B10TRPM8KDM4ELMNA | |
| SCHEMBL8550467 | 0.80 | CYP1A2 (0.50) | ALDH1A1HSD17B10TRPM8KDM4EMAPT | |
| SCHEMBL8549346 | 0.75 | LMNA (0.53) | ALDH1A1HSD17B10TRPM8KDM4ELMNA | |
| SCHEMBL8547177 | 0.74 | TRPM8 (0.38) | ALDH1A1HSD17B10TRPM8KDM4ELMNA | |
| SCHEMBL8547197 | 0.73 | TRPM8 (0.41) | ALDH1A1HSD17B10TRPM8KDM4ELMNA | |
| SCHEMBL8550254 | 0.73 | TRPM8 (0.46) | ALDH1A1HSD17B10TRPM8LMNAMAPT | |
| SCHEMBL8663874 | 0.72 | TRPM8 (0.43) | ALDH1A1HSD17B10TRPM8KDM4ELMNA | |
| SCHEMBL8548183 | 0.72 | SMN1; SMN2 (0.43) | ALDH1A1HSD17B10TRPM8KDM4ELMNA | |
| SCHEMBL8663140 | 0.72 | TRPM8 (0.46) | ALDH1A1TRPM8MAPTTSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |