Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551467 | 0.85 | GRM5 (0.36) | GRM5KDRIMPDH2MAPTNPC1 | |
| SCHEMBL8191280 | 0.85 | HTR1F (0.50) | GRM5MAPTPOLBALDH1A1HPGD | |
| SCHEMBL5906312 | 0.85 | HTR1F (0.51) | GRM5NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8549636 | 0.72 | HTR1F (0.51) | CA9MAPTPOLBRAB9AKDM4E | |
| SCHEMBL8548549 | 0.71 | HTR1F (0.50) | KDRMAPTPOLBRAB9AHTR1F | |
| SCHEMBL8549366 | 0.69 | TP53 (0.41) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8551686 | 0.69 | TP53 (0.40) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| Cadaverine Tartrate SCHEMBL8550421 | 0.68 | MAP1LC3B (0.41) | MAPT | |
| SCHEMBL8552580 | 0.68 | HTR1F (0.65) | MAPTPOLBNPC1RAB9AKDM4E | |
| SCHEMBL8547488 | 0.68 | HTR1F (0.53) | CA9MAPTPOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |