Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550020 | 0.85 | GAA (0.48) | ALDH1A1KDM4EPOLBGAATDP1 | |
| SCHEMBL8546509 | 0.84 | TGM2 (0.47) | ALDH1A1KDM4EPKMMAPTSMN1; SMN2 | |
| SCHEMBL8555909 | 0.81 | EGFR (0.33) | ALDH1A1KDM4EPKMPOLBGAA | |
| SCHEMBL8547481 | 0.80 | TGM2 (0.43) | ALDH1A1POLBTDP1MAPTSMN1; SMN2 | |
| SCHEMBL8557510 | 0.79 | LY96 (0.55) | ALDH1A1GAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8545460 | 0.79 | ALDH1A1 (0.34) | ALDH1A1GAATDP1MAPTSMN1; SMN2 | |
| SCHEMBL9408933 | 0.79 | PYGL (0.50) | ALDH1A1POLBHTTHPGDMAPK1 | |
| SCHEMBL10335578 | 0.78 | GAA (0.56) | ALDH1A1KDM4EPKMPOLBGAA | |
| SCHEMBL10335328 | 0.78 | GAA (0.56) | ALDH1A1KDM4EPKMPOLBGAA | |
| SCHEMBL8551807 | 0.77 | TGM2 (0.43) | ALDH1A1POLBGAATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |