Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 13/20 | 0.50 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549459 | 0.93 | PYGL (0.52) | PYGLDPEP1 | |
| SCHEMBL8549387 | 0.89 | DPEP1 (0.42) | PYGLDPEP1 | |
| SCHEMBL8546512 | 0.85 | VCAM1 (0.44) | HPGDPOLBHTTNPC1LMNA | |
| SCHEMBL8552907 | 0.84 | ALDH1A1 (0.47) | HPGDPOLBPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL8551077 | 0.83 | RAB9A (0.37) | PYGLHPGDMAPK1RAB9AALDH1A1 | |
| SCHEMBL8554286 | 0.82 | PYGL (0.42) | PYGLDPEP1HPGDPOLBHTT | |
| SCHEMBL8545460 | 0.82 | ALDH1A1 (0.34) | DPEP1NPC1MAPK1RAB9AALDH1A1 | |
| SCHEMBL8547481 | 0.80 | TGM2 (0.43) | POLBNPC1LMNAMAPK1RAB9A | |
| SCHEMBL8551807 | 0.80 | TGM2 (0.43) | DPEP1POLBHTTLMNAMAPK1 | |
| SCHEMBL8550135 | 0.79 | ALDH1A1 (0.47) | HPGDPOLBHTTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |