Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554406 | 0.88 | ACACB (0.43) | MAPTALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8547481 | 0.85 | TGM2 (0.43) | TGM2MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL8550135 | 0.84 | ALDH1A1 (0.47) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL8550978 | 0.84 | MAPT (0.46) | MAPTTHRBALDH1A1KMT2ALMNA | |
| SCHEMBL8551807 | 0.83 | TGM2 (0.43) | TGM2MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL8557510 | 0.82 | LY96 (0.55) | TGM2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8555056 | 0.81 | THRB (0.43) | TGM2THRBALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8550291 | 0.80 | ALDH1A1 (0.39) | TGM2MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL8549416 | 0.80 | TGM2 (0.47) | TGM2LMNASMN1; SMN2CYP1A2HDAC3 | |
| SCHEMBL5799213 | 0.79 | MAPT (0.51) | MAPTTHRBALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |