Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554560 | 0.85 | LY96 (0.48) | LY96ALDH1A1MAPTMTNR1AMTNR1B | |
| SCHEMBL8546509 | 0.82 | TGM2 (0.47) | ALDH1A1MAPTMTNR1AMTNR1BMEN1 | |
| SCHEMBL8550135 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL8150699 | 0.75 | MAPT (0.43) | LY96ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8152729 | 0.73 | POLB (0.43) | LY96ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8555564 | 0.73 | NFE2L2 (0.45) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL8554406 | 0.73 | ACACB (0.43) | ALDH1A1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL5378571 | 0.72 | MAPT (0.59) | LY96ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL20456245 | 0.71 | APLNR (0.58) | ALDH1A1MAPTGAA | |
| SCHEMBL9408929 | 0.71 | ZDHHC20 (0.43) | MTNR1AMTNR1BNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |