Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12491432 | 0.84 | MAPT (0.61) | ALDH1A1HTTSMN1; SMN2APPMAPT | |
| SCHEMBL4311452 | 0.83 | SMN1; SMN2 (0.48) | ALDH1A1HTTSMN1; SMN2APPMAPT | |
| SCHEMBL8552540 | 0.80 | MAPT (0.56) | ALDH1A1HPGDHTTSMN1; SMN2APP | |
| SCHEMBL14551144 | 0.77 | HTT (0.52) | ALDH1A1HTTSMN1; SMN2MAPTRAB9A | |
| SCHEMBL7951904 | 0.75 | ALDH1A1 (0.65) | ALDH1A1HPGDSMN1; SMN2MAPTKMT2A | |
| Ammonia Solution, Strong SCHEMBL8553360 | 0.74 | ALDH1A1 (0.59) | ALDH1A1HPGDSMN1; SMN2APPMAPT | |
| SCHEMBL1458965 | 0.74 | CHRNB2 (0.51) | ALDH1A1HTTSMN1; SMN2APPMAPT | |
| SCHEMBL1459521 | 0.74 | KDM4E (0.49) | ALDH1A1HTTSMN1; SMN2APPMAPT | |
| SCHEMBL2209951 | 0.72 | ACHE (0.46) | ALDH1A1HTTSMN1; SMN2APPMAPT | |
| SCHEMBL9379405 | 0.72 | RAB9A (0.48) | ALDH1A1HTTSMN1; SMN2APPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871619-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997024343-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-07-10 | — | — | WO | disclosed |