Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8550166 | 0.80 | ALDH1A1 (0.51) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL1745085 | 0.76 | MAOA (0.62) | MAPTRAB9AKMT2AMEN1LMNA | |
| SCHEMBL3337610 | 0.75 | KMT2A (0.59) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL12643697 | 0.72 | MAPT (1.00) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL12491432 | 0.71 | MAPT (0.61) | MAPTRAB9AKMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL28805026 | 0.71 | XDH (0.55) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL1459521 | 0.70 | KDM4E (0.49) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL1458965 | 0.70 | CHRNB2 (0.51) | MAPTRAB9AKMT2AMEN1LMNA | |
| SCHEMBL4311452 | 0.70 | SMN1; SMN2 (0.48) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL2209951 | 0.69 | ACHE (0.46) | MAPTRAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871619-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997024343-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-07-10 | — | — | WO | disclosed |