Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146842 | 0.84 | BRD4 (0.47) | HTR6SMN1; SMN2HTTMAPTGAA | |
| SCHEMBL8549554 | 0.84 | HTR6 (0.42) | MEN1KMT2AHTR6ALDH1A1SMN1; SMN2 | |
| SCHEMBL8931396 | 0.78 | BRD4 (0.48) | HTR6SMN1; SMN2HTTMAPTGAA | |
| SCHEMBL8546895 | 0.77 | MEN1 (0.43) | MEN1KMT2AALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL8550370 | 0.74 | KDM4E (0.41) | MEN1KMT2AALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL8550195 | 0.73 | MEN1 (0.44) | HIF1APTPN2PTPN1PTPN5MEN1 | |
| SCHEMBL8551076 | 0.71 | CNR2 (0.41) | MEN1KMT2AALDH1A1PKMHTT | |
| SCHEMBL6669755 | 0.66 | HTR1F (0.45) | HIF1AKMT2AALDH1A1HTTTSHR | |
| SCHEMBL19057714 | 0.65 | MEN1 (0.83) | HIF1APTPN1MEN1KMT2AALDH1A1 | |
| SCHEMBL23220383 | 0.64 | MEN1 (0.65) | HIF1APTPN1PTPN5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |