Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 16/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SCD | O00767 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552681 | 0.92 | DRD2 (0.42) | SCD5SCDLMNANPC1RAB9A | |
| SCHEMBL8547387 | 0.79 | HTR1A (0.42) | LMNA | |
| Hydrochloric Acid SCHEMBL8551657 | 0.79 | HTR1A (0.41) | MAPTLMNA | |
| SCHEMBL8545434 | 0.76 | DRD2 (0.40) | TP53MAPTLMNANPC1RAB9A | |
| SCHEMBL7815594 | 0.75 | SLC6A4 (0.46) | MAPTLMNAHTT | |
| SCHEMBL8546423 | 0.72 | SNCA (0.42) | LMNA | |
| SCHEMBL8551917 | 0.68 | SCD5 (0.62) | SCD5TP53MAPTLMNANPC1 | |
| SCHEMBL7814691 | 0.66 | SIGMAR1 (0.43) | MAPTHTT | |
| SCHEMBL7817070 | 0.66 | HTR1A (0.59) | — | |
| SCHEMBL1388436 | 0.65 | DRD4 (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822814-A4 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1998-12-09 | — | — | EP | disclosed |
| EP-0822814-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-02-11 | — | — | EP | disclosed |
| US-5668148-A | BENIGN PROSTATIC HYPERTROPHY | MERCK & CO., INC. (US) | 1997-09-16 | — | — | US | disclosed |
| WO-1996032938-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1996-10-24 | — | — | WO | disclosed |