Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644656 | 0.90 | HRH3 (0.39) | SIGMAR1 | |
| SCHEMBL8595580 | 0.90 | HTR7 (0.34) | — | |
| SCHEMBL8356623 | 0.88 | ITGB3 (0.38) | SIGMAR1 | |
| SCHEMBL8550693 | 0.85 | HTR2B (0.43) | SIGMAR1HTR2B | |
| SCHEMBL8355533 | 0.78 | ITGB3 (0.36) | — | |
| Bicarbonate SCHEMBL8589956 | 0.77 | DRD2 (0.33) | HTR2B | |
| SCHEMBL8644651 | 0.77 | ITGB3 (0.41) | — | |
| SCHEMBL8351077 | 0.77 | F10 (0.37) | — | |
| SCHEMBL8593632 | 0.75 | HTR2B (0.45) | SIGMAR1HTR2B | |
| SCHEMBL8552786 | 0.75 | HTR2B (0.45) | SIGMAR1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839147-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003072-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-30 | — | — | WO | disclosed |